Proteomics - Human Diseases and Protein Functions - T. Man, R. Flores (Intech, 2012) WW.pdf

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PROTEOMICS –

HUMAN DISEASES

AND PROTEIN FUNCTIONS

Edited by Tsz-Kwong Man

and Ricardo J. Flores

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Proteomics – Human Diseases and Protein Functions

Edited by Tsz-Kwong Man and Ricardo J. Flores

Subject Editors: Tsz-Kwong Man and Ricardo J. Flores

Published by InTech

Janeza Trdine 9, 51000 Rijeka, Croatia

Copyright © 2012 InTech

All chapters are Open Access distributed under the Creative Commons Attribution 3.0

license, which allows users to download, copy and build upon published articles even for

commercial purposes, as long as the author and publisher are properly credited, which

ensures maximum dissemination and a wider impact of our publications. After this work

has been published by InTech, authors have the right to republish it, in whole or part, in

any publication of which they are the author, and to make other personal use of the

work. Any republication, referencing or personal use of the work must explicitly identify

the original source.

As for readers, this license allows users to download, copy and build upon published

chapters even for commercial purposes, as long as the author and publisher are properly

credited, which ensures maximum dissemination and a wider impact of our publications.

Notice

Statements and opinions expressed in the chapters are these of the individual contributors

and not necessarily those of the editors or publisher. No responsibility is accepted for the

accuracy of information contained in the published chapters. The publisher assumes no

responsibility for any damage or injury to persons or property arising out of the use of any

materials, instructions, methods or ideas contained in the book.

Publishing Process Manager Martina Durovic

Technical Editor Teodora Smiljanic

Cover Designer InTech Design Team

First published February, 2012

Printed in Croatia

A free online edition of this book is available at www.intechopen.com

Additional hard copies can be obtained from orders@intechweb.org

Proteomics – Human Diseases and Protein Functions, Edited by Tsz-Kwong Man and

Ricardo J. Flores; Subject Editors: Tsz-Kwong Man and Ricardo J. Flores

p. cm.

ISBN 978-953-307-832-8

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Contents

Preface IX

Part 1

Proteomic Discovery of Disease Biomarkers

1

Chapter 1

Overview of Current Proteomic Approaches for

Discovery of Vascular Biomarkers of Atherosclerosis

3

Lepedda Antonio Junior,

Zinellu Elisabetta and Formato Marilena

Chapter 2

From Biomarker Discovery to

Clinical Evaluation for Early

Diagnosis of Lung Surgery-Induced Injury

33

Mei-Ling Tsai, Shu-Hui Chen,

Chih-Ching Chang and Ming-Ho Wu

Chapter 3

Urinary Exosomes for Protein Biomarker Research

49

Delfin Albert Amal Raj, Immacolata Fiume,

Giovambattista Capasso and Gabriella Pocsfalvi

Chapter 4

Circadian Proteomics and Its Unique Advantage

for Discovery of Biomarkers of Heart Disease

65

Peter S. Podobed,

Gordon M. Kirby and Tami A. Martino

Chapter 5

Exploring the Role of Biomarkers

for the Diagnosis and Management

of Traumatic Brain Injury Patients

89

Linda Papa

Part 2

Proteomic Analysis of Protein Functions

107

Chapter 6

Comparative Proteomics:

An Approach to Elucidating the

Function of a Novel Gene Called BRE

109

Kenneth Ka Ho Lee, Mei KuenTang,

John Yeuk-Hon Chan, Yiu Loon Chui, Elve Chen,

Yao Yao, Olivia Miu Yung Ngan and Henry Siu Sum Lee

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