GABA and the Basal Ganglia [Progress in Brain Research Vol 160] - J. Tepper, et al., (2007) WW.pdf - Bio Med 11 - hilakku

List of Contributors

E.D. Abercrombie, Center for Molecular and Behavioral Neuroscience, Rutgers University, 197 University

Avenue, Newark, NJ 07102, USA

G.W. Arbuthnott, Basal Ganglia Research Group, Department of Anatomy and Structural Biology,

School of Medical Sciences, University of Otago, P.O. Box 913, 270 Great King Street, Dunedin,

New Zealand

A. Arslan, Department of Clinical Neurobiology, University of Heidelberg, Im Neuenheimer Feld 364,

69120 Heidelberg, Germany

J. Baufreton, Laboratoire de physiologie et physiopathologie de la signalisation cellulaire, UMR CNRS

5543, Universite´ de Bordeaux 2, 146 Rue Le´ o Saignat, 33076 Bordeaux Cedex, France

M.D. Bevan, Northwestern University, Department of Physiology, Feinberg School of Medicine, 303

E. Chicago Avenue, Chicago, IL 60611, USA

J.P. Bolam, Medical Research Council, Anatomical Neuropharmacology Unit, Department of Pharma-

cology, University of Oxford, Mansﬁeld Road, Oxford, OX1 3TH, UK

J. Boyes, School of Life and Health Sciences, Aston University, Birmingham, UK

S. Charpier, Dynamique et Physiopathologie des Re´ seaux Neuronaux, INSERM U667, UPMC, Colle` ge de

France, 11 Place Marcelin Berthelot, 75231 Paris, Cedex 05, France

M.-F. Chesselet, Departments of Neurology and Neurobiology, The David Geffen School of Medicine at

UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA

J.M. Deniau, Dynamique et Physiopathologie des Re ´ seaux Neuronaux, INSERM U667, UPMC, Colle ` ge

de France, 11 Place Marcelin Berthelot, 75231 Paris, Cedex 05, France

G. Drew, Institute of Physiology and Pathophysiology and Interdisciplinary Center for Neurosciences

(IZN), University of Heidelberg, Im Neuenheimer Feld 326, D-69120 Heidelberg, Germany

P.C. Emson, The Babraham Institute, Babraham Research Campus, Cambridge, CB2 4AT, UK

M. Farrant, Department of Pharmacology, UCL (University College London), Gower Street, London

WC1E 6BT, UK

A. Galvan, Department of Neurology, School of Medicine and Yerkes National Primate Research Center,

Emory University, 954 Gatewood Road NE, Atlanta, GA 30322, USA

T. Goetz, Department of Clinical Neurobiology, University of Heidelberg, Im Neuenheimer Feld 364,

69120 Heidelberg, Germany

N.E. Hallworth, Northwestern University, Department of Physiology, Feinberg School of Medicine, 303

E. Chicago Avenue, Chicago, IL 60611, USA

O. Hikosaka, Laboratory of Sensorimotor Research, National Eye Institute, National Institute of Health,

49 Convent Drive, Bldg. 49, Rm. 2A50, Bethesda, MD 20892-4435, USA

K. Kaila, Department of Biological and Environmental Sciences and Neuroscience Center, Laboratory of

Neurobiology, University of Helsinki, P.O. Box 65 (Viikinkaari 1), FIN-00014 Helsinki, Finland

H. Kita, Department of Anatomy and Neurobiology, The University of Tennessee Memphis, 855 Monroe

Avenue, Memphis, TN 38163, USA

C.R. Lee, Center for Molecular and Behavioral Neuroscience, Rutgers University, 197 University Avenue,

Newark, NJ 07102, USA

M.S. Levine, Mental Retardation Research Center, The David Geffen School of Medicine at UCLA, 710

Westwood Plaza, 58-258 NPI, Los Angeles, CA 90095-1769, USA

P. Mailly, Neurobiologie des Signaux Intercellulaires, CNRS UMR 7101, UPMC, 4 Place Jussieu, 75005

Paris, France

N. Maurice, Dynamique et Physiopathologie des Re´ seaux Neuronaux, INSERM U667, UPMC, Colle` ge de

France, 11 Place Marcelin Berthelot, 75231 Paris, Cedex 05, France

J.F. McGinty, Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425,

USA

U. Misgeld, Institute of Physiology and Pathophysiology and Interdisciplinary Center for Neurosciences,

(IZN), University of Heidelberg, Im Neuenheimer Feld 326, D-69120 Heidelberg, Germany

A. Nambu, Division of System Neurophysiology, National Institute for Physiological Sciences, 38

Nishigo-naka, Myodaiji, Okazaki, 444-8585, Japan

J.L. Plotkin, Departments of Neurology and Neurobiology, The David Geffen School of Medicine

at UCLA, 710 Westwood Plaza, 58-258 NPI, Los Angeles, CA 90095-1769, USA

A. Schousboe, Department of Pharmacology and Pharmacotherapy, The Faculty of Pharmaceutical

Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark

T. Shindou, Basal Ganglia Research Group, Department of Anatomy and Structural Biology, School of

Medical Sciences, University of Otago, P.O. Box 913, Dunedin, New Zealand

J.M. Tepper, Center for Molecular and Behavioral Neuroscience, Rutgers University, 197 University

Avenue, Newark, NJ 07102, USA

H.S. Waagepetersen, Department of Pharmacology and Pharmacotherapy, The Faculty of Pharmaceutical

Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark

T. Wichmann, Department of Neurology, School of Medicine and Yerkes National Primate Research

Center, Emory University, 954 Gatewood Road NE, Atlanta, GA 30322, USA

J.R. Wickens, Basal Ganglia Research Group, Department of Anatomy and Structural Biology, School of

Medical Sciences, University of Otago, P.O. Box 913, 270 Great King Street, Dunedin, New Zealand

C.J. Wilson, Department of Biology, University of Texas at San Antonio, 6900 N. Loop 1604 W,

San Antonio, TX 78249, USA

W. Wisden, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD,

Scotland, UK

N. Wu, Mental Retardation Research Center, The David Geffen School of Medicine at UCLA, 710

Westwood Plaza, 58-258 NPI, Los Angeles, CA 90095-1769, USA

P. Wulff, Department of Clinical Neurobiology, University of Heidelberg, Im Neuenheimer Feld 364,

69120 Heidelberg, Germany

Y. Yanovsky, Institute of Physiology and Pathophysiology and Interdisciplinary Center for Neurosciences

(IZN), University of Heidelberg, Im Neuenheimer Feld 326, D-69120 Heidelberg, Germany

Preface

The genesis of this volume occurred during a car ride from Heathrow Airport to Oxford in the Spring

of 2003 when two of us (JPB and JMT) were discussing that, for a couple of neuroscientists who were

mostly interested in dopaminergic systems in the basal ganglia, we both found ourselves spending what

seemed to us an inordinate amount of time doing experiments on GABAergic basal ganglia neurons and

pathways. One of us mentioned to the other a little red book called ‘‘GABA and the Basal Ganglia’’ that was

published by Raven Press in 1981 as Volume 30 of the Advances in Biochemical Psychopharmacology series.

Both of us remembered this little camera-ready book edited by Gaetano DiChiara and Gian Luigi Gessa

with great fondness, as it contained many chapters by some of the top names in basal ganglia research.

Both of us had bought that book with our own money. As we were both of modest means in 1980, to buy a

book with our own money indicated that there was something special about the book. We both thought

that it had been a great investment and that little book proved very inﬂuential to us as it summarized much

of the state-of-the-art of knowledge about the GABAergic mechanisms in the basal ganglia as it existed

around 1980.

In the Spring of 2004 Elizabeth Abercrombie and I were fortunate enough to be able to spend our

sabbatical leave in Paul Bolam’s laboratory. One day, the three of us were having lunch (at one of the many

great pubs around Oxford) and the subject of ‘‘GABA and the Basal Ganglia’’ came up again. It turned out

that Elizabeth also was quite familiar with the book and felt similarly about it. We began to discuss

the current state of knowledge concerning the biochemistry, anatomy and physiology of GABA in the

basal ganglia and realized that in the 25 years since the original ‘‘GABA and the Basal Ganglia’’ was

published, our knowledge of virtually all aspects of GABAergic function had taken giant leaps forward.

Back in 1980 there was only a single GABA receptor known and the internal microstructure of the

neostriatum was completely unknown. The GABAergic nature of some of the basal ganglia pathways was

uncertain. Whole-cell recording did not exist, nor did in vivo microdialysis, biocytin or neurobiotin

labeling, PHA-L tract tracing, or much of the huge host of modern neurobiological techniques that have

enabled us to make so much progress in understanding the structural organization of the basal ganglia over

the past 25 years.

Thus the three of us decided that the time was right for another volume on the subject of GABA and the

Basal Ganglia. We had several additional meetings where we hashed out what chapters ought to be

included and which subjects should be covered in those chapters. Finally we made a wish list of the authors

we would like to write each chapter, and selected one or two back-up authors in case our ﬁrst choice

declined. In each case, the author we selected was a widely cited, internationally renowned authority on the

nucleus or pathway to which we wished to assign them. We also decided that, to make the volume as self-

contained as possible, we should also invite experts on GABA itself and GABA receptors. We then

approached Elsevier with our idea and waited. We were thrilled when Elsevier gave approval to our outline

and told us that the book would be published as part of their excellent Progress in Brain Research series. We

then began contacting the authors and to our amazement and delight the response was unprecedented. Of

the 16 authors we contacted, 15 wrote back that they would be delighted to contribute. The result is the

vii

viii

volume you hold in your hand. We hope it has as great an impact and proves to be as useful for the current

generation of neuroscientists studying the basal ganglia as the little red book was for us at the beginning of

our careers 25 years ago.

James M. Tepper

Elizabeth D. Abercrombie

J. Paul Bolam

Contents

List of Contributors . .......................................................

Preface . . . ..............................................................

vii

Section I. Fundamentals of GABA in the Basal Ganglia

1. Basal ganglia macrocircuits

J.M. Tepper, E.D. Abercrombie and J.P. Bolam (Newark, NJ, USA

and Oxford, UK) . ...............................................

2. GABA: Homeostatic and pharmacological aspects

A. Schousboe and H.S. Waagepetersen (Copenhagen, Denmark) . . . ...........

3. GABA A receptors: structure and function in the basal ganglia

T. Goetz, A. Arslan, W. Wisden and P. Wulff (Heidelberg, Germany

and Aberdeen, UK) . . . ...........................................

4. GABA B receptors: structure and function

P.C. Emson (Cambridge, UK) .......................................

5. The cellular, molecular and ionic basis of GABA A receptor signalling

M. Farrant and K. Kaila (London, UK and Helsinki, Finland) ...............

Section II. GABAergic Microcircuits of the Basal Ganglia

6. GABAergic inhibition in the neostriatum

C.J. Wilson (San Antonio, TX, USA). . . ...............................

7. Globus pallidus external segment

H. Kita (Memphis, TN, USA) ....................................... 111

8. Globus pallidus internal segment

A. Nambu (Okazaki, Japan) . ....................................... 135

9. The pars reticulata of the substantia nigra: a window to basal ganglia output

J.M. Deniau, P. Mailly, N. Maurice and S. Charpier (Paris, France). ........... 151

GABA and the Basal Ganglia [Progress in Brain Research Vol 160] - J. Tepper, et al., (2007) WW.pdf

Plik z chomika:

Inne pliki z tego folderu:

Inne foldery tego chomika: